Equivocal sequences that are predicted to be 伪-helical from amino acid preference but are found to be -strand from x-ray diffraction of their respective proteins, and equivocal sequences that are predicted to be -strand but found to be a-helical, are shown by circular dichroism (CD) to ...
Active nuclear import of Ran exchange factor RCC1 is mediated by importin α3. This pathway is essential to generate a gradient of RanGTP on chromatin that directs nucleocytoplasmic transport, mitotic spindle assembly and nuclear envelope formation. Here
Special AT-Rich Sequence-Binding Protein 2 (Satb2) is expressed in neurons of all layers and is indispensable for the formation of the corpus callosum12,13. In the murine brain, Satb2-expressing cells are born during a protracted period of development14, including both earlier- and later-...
Protein Structure Proteins are made of smaller monomers known as amino acids. Dependent on the order of amino acids, the protein can have radically different functions. Amino acids are generally classified by their polarity. Answer and Explanation:1 ...
The complete amino acid sequence of a fatty acid-binding protein from human heart was determined by automated Edman degradation of CNBr, BNPS-skatole [3'-b... GD Offner,P Brecher,WB Sawlivich,... - 《Biochemical Journal》 被引量: 148发表: 1988年 Cross-beta Order and Diversity in Nanoc...
Replacement of either TRAP220 LXXLL motif with the corresponding 13 amino acids of SRC1 LXM2 strongly enhanced the interaction of the TRAP220 NID with the estrogen receptor. Mutational analysis revealed combinatorial effects of the LXM1 core and flanking sequences in the determination of the NR ...
Responses to these hormones are mediated by transcription factors of the bri1-EMS suppressor 1/brassinazole resistant 1 subfamily, and BRs activate these factors by impairing their inhibitory phosphorylation by GSK3/shaggy-like kinases. Here we show that BRs induce nuclear compartmentalization of ...
Altered coding sequence of the merlin tumor suppressor in an extended pedigree JAMA, 270 (1993), pp. 2316-2320 CrossrefView in ScopusGoogle Scholar [3] A.M. Petrilli, C. Fernández-Valle Role of Merlin/NF2 inactivation in tumor biology Oncogene, 35 (2016), pp. 537-548 CrossrefView in ...
Data files were searched against the gencode.v36.pc_translations protein database with sequences for mKO2 and mAG proteins manually added to the fasta file. The Sequest HT search algorithm was used, with precursor and fragment mass tolerances set to 10ppm and 0.6 Da, respectively. The ...
Using this method, it has been found that the protein concentration, phosphate concentration and pH of potassium phos- phate play a role in the particle formation process15,19. The amino acid sequence of the recombinant silk also seems to be a critical determinant of the particle properties28....