This further stresses the need for rigorous standardisation of commercial reagents and analytical procedures, as well as the introduction of external quality assessment (EQA) programs, and a complete definition of operative protocols adjusted to the sensitivity and specificity of the various methods....
We tested this hypothesis by depleting neutrophils in neonates with the 1A8-clone monoclonal antibody (which specifically recognizes Ly6G, a pan-neutrophil marker), followed by IP challenge with Spn. In the 1A8-treated neonates, an approximate 50% reduction in blood neutrophil numbers was ...
An important element in studies aiming to detect the prevalence of parasites in a population or commu- nity is the use of a sensitive and accurate methodology for detecting parasites. During the past few decades, the application of DNA sequencing and the definition of cytochrome ...
Following from the definition that 1 WLM is the exposure to potential αenergy of radon progeny from 1 month (170 h) of irradiation at 3,700 Bq/m3, the RBM-absorbed dose at the cumulative radon dose of 1 WLM can be estimated to be 0.0139 mGy. Likewise, RBM-absorbed dos...
Xipayi Kui Jie’an (KJA), a type of traditional Uygur medicine (TUM), has shown promising therapeutic effects in Ulcerative colitis (UC). Owing to the complexity of TUM, the pharmacological mechanism of KJA remains vague. Therefore, the identification of complex molecular mechanisms is a major...
The t-test procedure was performed using each asthma definition yielding two lists of differentially expressed genes at α=0.05. Results were evaluated without multiple testing correction. As single domain clustering has previously been shown as a successful method for understanding disease etiology, ...
A much wider definition of biomonitoring also includes biomarkers that do not carry chemical structure information (a “unique signature”) that enables the researcher to link a biomarker value to a specific external factor. Biomonitoring consists of standardized protocols for the periodic detection of ...
(P = 0.00021) and was seen more commonly in patients with early infusion reactions (P = 2x1016).ConclusionThe PANTS study has provided a real world estimate of PNR and associated risk factors in a large prospective cohort using a simple clinical and biochemical definition at week 14 that ...
Although the biological definition of bleb is well established, a translation into quantitative terms admits different formulations. Here, we estimate the number of blebs by counting the number of regions of negative local curvature k along the nuclei perimeter. To avoid spurious results due to ...
(Sigma-Aldrich, St. Louis, MO, USA) as a substrate in McIlvaine’s buffer (0.1 M citric acid and 0.2 M Na2HPO4; pH 2.0 to pH 8.0) or 0.1 M Gly-HCl buffer (pH 1.0 to pH 3.0) at 37 °C for 1 hour as described previously49,54. Chia unit definition was also ...