Here, in Round 2, (Br, H, H ) beats (O, O, O) since Br has a higher atomic number than O. (Where’d we get that “third oxygen” ? The C-O pi bond makes O a “phantom atom” for nomenclature purposes.) 4. Now Trace A Path From Priorities 1-2-3 To Determin...
Consequently, OR ligand (odorant) recognition exhibits peculiar activation properties: each single OR can be activated by a large number of ligands, which translates into a cytosolic G protein response level that depends on the respective ligand bound23. Contrary to the seemingly unspecific ligand ...
So, we do not compare layers 2 and 3 which would’ve given the priority to the carbon with a Br since Br has a higher atomic number than oxygen. Because the oxygen is connected to a carbon closer to the chiral center, it gives the priority to that carbon regardless of what is connect...