ReportingEconomic impactOverviewAdverse drug reactions (ADRs) occur in about 5% of drug-treated patients. Hospital admissions are caused by ADRs in 5% of patients and roughly 2% of hospitalized patients will experience an ADR. The economic burden of ADRs can only be estimated. Type A reactions ...
Tools to accurately predict and detect adverse drug reactions (ADR) in elderly patients have not been developed. We aimed to identify and evaluate reports on tools that predict and detect ADR in elderly patients (≥ 60 years). In this review, we followed the Preferred Reporting Items for Sy...
The frequency of ADR causing admissions detected by employing a computer-assisted approach using an ICD-10 coding system was 0.2% (1/520), and no patient admitted due to ADRs was reported to the national reporting system (0/520). The recognized frequency of ADR related admissions also depends...
Detection, Identification and Warning Detection, Identification, Location, and Reporting Detection, Intercept, Passive Submarine Detection, Intervention and Monitoring of COPD Detection, Isolation, Recovery Detection, Measurement and Control Relay Détection, Mesure et Assistance Électronique ...
Adverse drug events (ADEs) detection and assessment is at the center of pharmacovigilance. Data mining of systems, such as FDA's Adverse Event Reporting Sy... V Santiago,H Rave,S Lourdes,... - 《Plos One》 被引量: 45发表: 2012年 Electronic medical records in diabetes consultations: partic...
We used the Side Effect Resource (SIDER) database to select 2663 drug-ADR pairs to investigate unknown drug-induced ADRs. The reporting odds ratio (ROR) value was calculated for the drug-exposed and non-exposed groups of drug–ADR pairs, and 19 potential pairs showed significant signals. ...
Data that have been previously used in ADR research came from the Federal Drug Administration's Adverse Event Reporting System (FAERS) [5, 6] and clin- ical electronic medical records. Because of the privacy protection, those kinds of databases are not fully open access. Moreover, those ...
GBM and RF identified four of the five ADRs earlier than their inclusion on the drug label, while ROR and IC did not detect any ADRs before their official updates. Wang et al. [27] compared conventional statistical methods (including proportional reporting ratio (PRR), ROR, and IC) with a...
Decision support methods for the detection of adverse events in post-marketing data Spontaneous reporting is a crucial component of post-marketing drug safety surveillance despite its significant limitations. The size and complexity of som... M Hauben,A Bate - 《Drug Discovery Today》 被引量: 206...
Background The detection of signals of adverse drug events (ADEs) has increased because of the use of data mining algorithms in spontaneous reporting systems (SRSs). However, different data mining algorithms have different traits and conditions for application. The objective of our study was to exp...