33, we also assessed the number of symmetric and asymmetric events in 3D epidermal organotypic cultures under control, Dsg1, Tctex-1, or Dsg2 knockdown conditions. Silencing Dsg1, Tctex-1, or Dsg2 did not significantly affect the number of symmetric or asymmetric...
3D). Because cadherins are not functional in LCM (49, 50), it may be that Ca2+ switching experiments are not sufficient to show that cross-linking of desmosomal cadherins requires cell-cell adhesion; cis interaction may occur, and cross-linking may be obtainable in normal culture medium ...