Factorial designs can require very large sample sizes, especially as the number of factors grows. To reduce required sample sizes, fractional factorial designs use a technique referred to as confounding. Confounding occurs when two main effects or interactions cannot be separated; if either is signifi...
There are many purposes of DoE application: screening studies to determine the most influential factors affecting the product/process being studied; full or fractional designs to quantifyfactorialeffects; in-depth response surface studies particularly useful for optimization; mixture designs, etc. The sele...