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which forms a β-hairpin structure at the site of interaction in the X-ray structure (PDBid: 1G3J)37. The β-catenin binding domain of xTCF3 aligns very closely with the sequence of human TCF4 (Supplementary Fig.1). This cleft is also adjacent to the G13ANDE17region of the hTCF4 β...
In this study, a comparative analysis has been conducted to explore the correlation between geometric design elements and their impact on WWD incidents at parclo interchanges. A total of 75 parclo interchange terminals from 13 states were monitored. A comprehensive dataset of over 5000 h of ...
The findings of the Rotterdam Study have been presented in over 1200 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives ...
Prediction and analysis of the structure-based CatA redesign to increase enzyme activity Based on the crystal structure of CatA fromAcinetobactersp. ADP121, as well as data from the Protein Data Bank (PDB ID: 1DLT), the substrate-binding pocket model of wild-type CatA was reconstructed using ...
Another DE-based CNN (DE-CNN) was proposed in [74] for performing sentiment analysis in Arabic. Each parameter to be optimized (i.e., filter sizes, number of neurons, number of filters per convolutional filter sizes, initialization mode, and dropout rate) was stored in every dimensional ...
Versions Notes Abstract It has been challenging for designers to identify the appropriate design parameters that would reduce building energy consumption while achieving thermal comfort for building occupants. This study aims to determine the most important architectural building design parameters (ABDPs) th...
applied sciences Review Spatial Audio for Soundscape Design: Recording and Reproduction Joo Young Hong 1,*, Jianjun He 2, Bhan Lam 1, Rishabh Gupta 1 and Woon-Seng Gan 1 1 School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore; blam002@e....