The preparation of the carboxylic acids derived from indane represented by the formula: in which R has the meaning given in Claim 1, in the free form, of their therapeutically acceptable salts, and of certain of their amino esters and carboxamides are described. Indane which is free of ...
Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient A carboxylic acid derivative of formula (I): wherein Ris —COOH, —COOR, etc.; A is a single bond, alkylene, etc.; Ris alkyl, alkoxy, etc.; B is a carbocyclic ring or a heterocyclic ring;...
CARBOXYLIC ACID DERIVATIVE OR SALT THEREOFIt is intended to provide a compound which has an anticoagulant effect based on the inhibition of the activated blood coagulation factor VII and, therefore, is useful as a blood coagulation inhibitor or a preventive/remedy for diseases caused by thrombus or...
A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I); <Chemistry id="CHEM-US-00001"> </Chemistry>(wherein all symbols are as defined in the specification), a non-toxic acid thereof or a hydrate thereof as active ingredient. ;Because of ...
The invention provides a carboxylic acid derivative compound. The compound as shown in the formula (I) or the pharmaceutically acceptable salt thereof provided by the invention not only can reduce the level of triglyceride in high fat model animal blood, but also has the good function of ...
Novel tetrahydrofurancarboxylic acid derivatives of the general formula I <IMAGE> (I) or polymers of these containing units of the formula II <IMAGE> (II) where the radicals R independently of one another are each C1-C4-alkyl, cyclohexyl or phenyl, m is from 0 to 3, n is 1 or 2, an...
Derivative of pyrazole carboxylic acid, useful as a starting material in the synthesis of the derivative and herbicide containing composition That is a Derivative of pyrazole herbicide activity with high selectivity of the formula (i), wherein: R1 is alkyl, alquenilo ohaloalquilo; R2 is H, alk...
PREPARATION:A carboxylic acid expressed by formula II or III (A is OH, halogen or active ester) or derivative thereof is reacted with a nitrophenol or nitroaniline expressed by formula IV in the presence or absence of a base (e.g., alkali hydroxide) in water or an organic solvent below ...
NEW MATERIAL:The compound of formula I (Z is group of formula II or formula III; A is group of formula IV, formula V, etc.) and its salt. EXAMPLE:cis-2-[( 3,5-Bistrifluoromethylphenyl )-aminocarbonyl]-cyclohexane-carboxylic acid. USE:It has antispasmodic action, antianoxic action, ant...
Several acyclic and cyclic boronic acid/ester-based BLIs were disclosed in 2013. For example, the 1,2,3-traizolecarboxylic acid substituted amido boronic acid derivatives represented by 31 have been reported to inhibit class A (CTX-M-15, SHV-12, KPC-2), class C, and some class D (Oxa...