Malet-Sanz et al. also adapted their method to the preparation of arylsulfonyl chlorides in a Meerwein chlorosulfo-de-diazotisation reaction (Scheme 7).15The challenge for this reaction setup was the incompatibility of the original reaction conditions with the flow setup due to precipitates and co...
According to a study which reported the experimental determination of the solubility of 16 pharmacologically active substances at pH = 1.2, 4.5, and 6.8 by the shake-flask method and their classification in highly soluble and not highly soluble molecules, at pH = 6.8, which is a pH value simi...
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An enormous challenge associated with using integer-order derivatives (first and second derivatives) to preprocess spectra is that it is difficult to capture the gradual tilt or curvature of spectra; notably, the corresponding spectral regions may contain helpful information for constraining the target ...
The importance of space and time for signal processing in neuromorphic agents: The challenge of developing low-power, autonomous agents that interact with the environment. IEEE Signal Process. Mag. 2019, 36, 16–28. [Google Scholar] [CrossRef] [Green Version] Luo, Y.; Wan, L.; Liu, J....
5.7. Immunization of Mice and Challenge with BoNT/F SPF female Balb/c mice at 6~8 weeks old were randomly divided into different groups (n = 10 per group). Single antigen (1 or 10 µg/dose) and combined antigens (0.5 or 5 µg for each/dose) were diluted in sterile PBS, and...