graded potential barrierWKB methodmodified airy functionsGeneral expressions of tunneling probability for arbitrarily graded potential barriers are rigorously derived using the modified Airy functions. Three types of graded potential barriers for which......
A major barrier to progress is the overly broad definition of the syndrome, which encompasses a vast, multidimensional array of clinical and biological features. Different combinations of these features may naturally cluster into previously undescribed subsets or phenotypes that may have different risks ...
3. The mode of action (MoA) for carcinogenicity 4. Oral studies in mammals with specific emphasis on local irritation 5. Studies with oral exposure in birds, specific emphasis on local irritation (Table 1) 6. Studies with oral exposure, potential systemic effects 7. Reproductive and developmenta...
The blood-brain barrier (BBB) is crucial to the health of the brain and is often compromised in neurological disease. Moreover, because of its barrier properties, this endothelial interface restricts uptake of neurotherapeutics. Thus, a renewable source of human BBB endothelium could spur brain res...
The proportion of organoids with intact barrier integrity (organoids without inulin signals inside the lumen) of each group was calculated for quantification analysis. Ciliary beat frequency analysis Organoids were seeded into eight-well glass-bottom slides (ibidi, 80806) and differentiated toward the...
(days 3–9 of differentiation) of intercellular structures important for intestinal barrier function. Adherens junction (AJ), tight junction (TJ), and desmosomes (D) structures are seen in both canine enteroids and native jejunum. On day 3, the developing tight junction had dilated paracellular ...
Superficial cells are characterised by apical expression of tissue-restricted transmembrane uroplakins that contribute to transcellular barrier function [10], [36], whilst paracellular barrier function is provided by well-developed intercellular tight junctions [16], [44]. In human urothelium, ...
Initially classified as passive and merely supporting cells, today, astrocytes are known as active components of brain development, homeostasis and function. These features include the regulation of blood flow, blood brain barrier formation and function, and synapse formation and elimination1,2,3,4. ...
Induced pluripotent stem cells (iPSCs) have considerably impacted human developmental biology and regenerative medicine, notably because they circumvent the use of cells of embryonic origin and offer the potential to generate patient-specific pluripotent stem cells. However, conventional reprogramming protocol...
Clearly, a pair-merged structure is not a barrier for movement, and Internal Set-MERGE could apply freely across derivational dimensions in principle. As for the contrast between nominal and verbal domains, several possibilities suggest themselves. For the impossiblewh-movement ofyoungout of ⟨young...