graded potential barrierWKB methodmodified airy functionsGeneral expressions of tunneling probability for arbitrarily graded potential barriers are rigorously derived using the modified Airy functions. Three types of graded potential barriers for which......
Lippmann et al. present a protocol for differentiating human pluripotent stem cells into blood-brain barrier endothelial cells. The cells should be useful for studying this endothelial barrier, including screening for drugs that can cross from the blood
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. The blood-brain barrier (BBB) is crucial to the health of the brain and is often compromised in neurological disease. Moreover, because of its barrier prop... ES Lippmann,SM Azarin,JE Kay,... - 《Nature...
3. The mode of action (MoA) for carcinogenicity 4. Oral studies in mammals with specific emphasis on local irritation 5. Studies with oral exposure in birds, specific emphasis on local irritation (Table 1) 6. Studies with oral exposure, potential systemic effects 7. Reproductive and developmenta...
Hobart [9] simulated the threshold potential of movement which was represented by the minimum energy difference between stable and unstable configurations of dislocation in the polycrystalline Cu. Graham [10] calculated the Peierls barrier through the addition of a non-harmonic potential in BCC (body...
Brain microvascular endothelial cells (BMECs) can be differentiated from human induced pluripotent stem cells (iPSCs) to develop ex vivo cellular models for studying blood-brain barrier (BBB) function. This modified protocol provides detailed steps to derive, expand, and cryopreserve BMECs from huma...
A major barrier to progress is the overly broad definition of the syndrome, which encompasses a vast, multidimensional array of clinical and biological features. Different combinations of these features may naturally cluster into previously undescribed subsets or phenotypes that may have different risks ...
Initially classified as passive and merely supporting cells, today, astrocytes are known as active components of brain development, homeostasis and function. These features include the regulation of blood flow, blood brain barrier formation and function, and synapse formation and elimination1,2,3,4. ...
Induced pluripotent stem cells (iPSCs) have considerably impacted human developmental biology and regenerative medicine, notably because they circumvent the use of cells of embryonic origin and offer the potential to generate patient-specific pluripotent stem cells. However, conventional reprogramming protocol...
Clearly, a pair-merged structure is not a barrier for movement, and Internal Set-MERGE could apply freely across derivational dimensions in principle. As for the contrast between nominal and verbal domains, several possibilities suggest themselves. For the impossible wh-movement of young out of ⟨...