Complex relationships between depression and chronic pain have been reported in previous studies. However, only a few neuroimaging studies have investigated similarities and differences in neural systems underlying them. We examined the brain functions i
Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation. J Neurosci 22: 10072–10077. Article CAS PubMed PubMed Central Google Scholar Bartsch D, Casadio A, Karl KA, Sero...
6,65–67]. Inflammatory triggers induce 'neuraxes', that is, ascending neural pathways, which convey information about metabolic, gastro-intestinal and cardiovascular challenges to brain regions that mediate stress-related behaviors [68,69]. For example, infection and immune activation activate...
The microbiota–gut–brain axis Sections Figures References Abstract Background Materials and methods Results Discussion Conclusions Availability of data and materials Abbreviations References Acknowledgements Funding Author information Ethics declarations Additional information Supplementary Information Rights and permi...
and maintenance of normal estrogen levels is important for several brain regions vulnerable to age-related changes158(e.g., the prefrontal cortex (PFC) and hippocampus)134,159,160. Similarly, age-related reduction in dehydroepiandrosterone (DHEA) has been linked to depression, cognitive decline, re...
Lewine RR, Hudgins P, Brown F, Caudle J, Risch SC (1995) Differ- ences in qualitative brain morphology findings in schizophrenia, major depression, bipolar disorder, and normal volunteers. Schizo- phr Res 15:253-259.Lewine RR, Hudgins P, Brown F, Caudle J, Risch SC. Differences in...
Brain perfusion scintigraphy with 99mTc-HMPAO or 99mTc-ECD and 123I- -CIT single-photon emission tomography in dementia of the Alzheimer-type and diffuse ... E Donnemiller,Jutta Heilmann… - 《Eur J Nucl Med》 被引量: 375发表: 1997年 Regional 133Xenon cerebral blood flow and cerebral 99mTc...
How sleep deprivation affects gene expression in the brain: a review of recent findings. The identification of the molecular correlates of sleep and wakefulness is essential to understand the restorative processes occurring during sleep, the ce... C Cirelli - 《Journal of Applied Physiology》 被引...
Finally, we discuss the failure of current first-line treatments to alleviate attention impairments in MDD and review evidence for more targeted pharmacological, brain stimulation, and behavioral interventions. By synthesizing findings across disciplines and delineating avenues for future research, we aim ...
(HPA axis, immuno-inflammatory activation, neuroendocrine regulators of energy metabolism including leptin and insulin, and microbiome) and brain circuitries integrating homeostatic and mood regulatory responses. Furthermore, the review addresses interventional opportunities and questions to be answered by ...