Changes in the upstream mediators of FoxOs including brain-derived neurotrophic factor (BDNF) and protein kinase B have been associated with depressive disorder and the antidepressant agents are known to alter the phosphorylation of FoxOs. Moreover, FoxOs might be regulated by serotonin or ...
The findings provide new 17 Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB et al. Physical activity, exercise, and inflammatory markers in older adults: findings from the health, aging and body composition study. J Am Geriatr Soc 2004; 52: 1098–1104. 18 Reuben...
CGRP: calcitonin-gene-related peptide; PACAP: pituitary adenylate cyclase-activating polypeptide; MDD: major depressive disorder; Ab: monoclonal antibody; VPAC1-R: vasoactive intestinal polypeptide receptor 1; VPAC2-R: vasoactive intestinal polypeptide receptor 2; PAC1-R: pituitary adenylate cyclase-...