To address this question, we performed mating preference tests using a light source that was covered with a sharp cut filter (SC64; cutoff <640 nm). We found that female birds were unable to distinguish between intact and castrated males (Supplementary Fig. S5), suggesting that female ...
A tunnel was excavated using the miniature TBM in a cubical rock specimen loaded in the true-triaxial cell; then the confining stress was increased in stages to values above the rock unconfined compressive strength. Strain gauges embedded in the rock specimen and a digital borehole caliper ...
Joy NakawesiSébastien ThisJulia Hutter...+13Katharina Lahl Mucosal Immunology Jan 2021 17被引用 0笔记 共1个版本 摘要原文 Secretory intestinal IgA can protect from re-infection with rotavirus (RV), but very little is known about the mechanisms that induce IgA production during intestinal virus inf...
Antibiotics expand the resistome in the lower GI tract Importantly, the effect of antibiotics on the gut resistome was previously reported using stool samples but not through direct sampling. Therefore, we next analysed the resistome of 21 healthy (that is, no active infection) adults who received...
Using Shh medulloblastoma as model, we show here that at clinically relevant concentrations, phenformin elicits a significant therapeutic effect through a redox-dependent but complex I-independent mechanism. Phenformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD), a component of the ...
Kubeczko, MarcinPolakiewicz-Gilowska, Annawiderska, KatarzynaLeniak, AleksandraMianowska-Malec, Martaanoszka, BarbarbaChomik, KonstantyGrandys, BarbaraLisovska, NatalyaBobek-Billewicz, BarbaraFrontiers in Oncology
Joshua and Fury are set to finally share the ring this year in a massive showdown between two British rivals, who currently hold every major world heavyweight belt between them. Promoter Eddie Hearn has admitted that clearance for a 'full capacity' attendance would be...
reader (Hitachi Hi Tec,Ibaragi,Japan) at the following wavelengths: excitatio n wavele ngth,490 n m;emissio n wavelength,53 0 ri m ;and bandwidth,5 n m.BB F (Y m1 min g ) was calculated using the mean fl uorescence intensity values for the bladder ( FI⋯ ,) and the ...
We performed three independent screens using aNAA35-KO query cell line to establish a high-confidence GI dataset for the major NatC auxiliary subunit. The reproducibility of the double-mutant fitness effects (log2-fold change, LFC) between the threeNAA35screens were strongly correlated (pairwiser...
Cells were lysed (50 mM Tris (pH 7.4), 150 mM NaCl, 1% Triton X-100, 50 mM NaF, 2 mM MgCl2, 1 mM Na3VO4 and protease inhibitor cocktail (Roche)) and cleared by centrifuging at 13,000xg at 4 °C, after which protein concentrations were determined using a BCA protein assay (...