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英文名称:Deoxyhypusine synthase/DHS Protein, Human (His)品牌厂商性质产地货期价格 MedChemExpress (MCE) 生产商 美国 现货 ￥1070 性能特点 脱氧马尿苷合酶 (DHS) 蛋白在亚精胺的 NAD 依赖性氧化裂解中起着至关重要的作用,随后亚精胺的丁胺部分转移到 eIF-5A 前体蛋白的 ε-氨基上。关键是赖氨酸。Deoxy...
Deoxyhypusine synthase (DHS) catalyzes the post-translational modification of eukaryotic translation factor 5A (eIF5A) by the polyamine, spermidine, that converts one specific lysine residue to deoxyhypusine [N (epsilon) -4-aminobutyl(lysine)], which is subsequently hydroxylated to hypusine [N (...
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Fig. 1. Evolutionary origin of homospermidine synthase (HSS) by duplication of the gene encoding deoxyhypusine synthase (DHS). eIF5A(lys), eukaryotic initiation factor 5A precursor protein with unmodified lysine residue that is only bound by DHS, but not by HSS; eIF5A(dhp), eIF5A protein wit...
Results:Trypanosomatid DHS activity is... S Nguyen,DC Jones,S Wyllie,... - 《Journal of Biological Chemistry》 被引量: 35发表: 2013年 New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase Deoxyhypusine synthase (DHPS) is the primary enzyme responsible for the hypusine modification ...
E-mail,krkang@gaechuk.gsnu.ac.kr Accepted8 December2003 Abbreviations: DHS,deoxyhypusinesynthase;eIF5A,eukaryotic initiationfactor5A Abstract Deoxyhypusineis a modifiedlysine andformed posttranslationallyto bethe eukaryoticinitiation factoreIF5A by deoxyhypusinesynthase,employ- ingspermidineas butylamine donor....
DHSNicotiana benthamianaVIGSsenescencepromoting growthA cDNA fragment corresponding to deoxyhypusine synthase gene NbDHS was isolated and cloned into potato virus X (PVX) vector for functional analysis in Nicotiana benthamiana by using virus-induced gene silencing (VIGS). Plants agroinfected with ...
Hypusine is formed posttranslationally by deoxyhypusine synthase (DHS) and deoxyhypu... Yeon,Sook,Kim,... - 《Faseb Journal》 被引量: 17发表: 2007年 Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination Han et聽al. describe...
Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual... DHS) catalyzes the transfer of the 4-aminobutyl moiety of spermidine to the -amino group of one specific lysine residue in eIF-5A to form ...