Thus, DNA preserves the genetic code in a sometimes harsh and damaging environment and has an effective means to reproduce for cell division. The remarkable complexity of human existence emerges from a chemical structure that is stable and effectively replicated. This chapter is concerned with the ...
result from a non-conventional CH-O hydrogen bond between fucose H-5 and the ring oxygen of the galactosyl residue (Supplementary Fig.5)46. Another consequence of this ‘closed conformation’ is the proximity of the fucose H-6 and galactose H-2 positions, which is believed to provide hydroph...
EPR analysis of the protein reduced by either chemical397or enzymatic398means confirmed that the stoichiometric quantities of iron and sulfur detected in the enzyme form a [2Fe–2S] center that exhibits slightly rhombic symmetry (g 1=2.012, g 2=1.950, g 3=1.932) and resembles that found in ...
Quenching is an effective means to harden carbon iron steels. If not carefully, the steels can easily break due to the rapid crystal structural change during quenching. An atomic packing factor is an important parameter to explain ...
It is also possible to resolve the 4-hydroxycyclopentenone racemate (36) by microbiological means. Thus, treatment of the 4-O-alkanoyl or aroyl derivatives (37) (R12=aryl or alkyl) of racemate (36) (preferably the 4-O-acetyl and 4-O-propionyl derivatives) with an appropriate microorganism...
It is also possible to resolve the 4-hydroxycyclopentenone racemate (XXXVIII) by microbiological means. Thus, treatment of the 4-O-alkanoyl or aroyl derivatives (XXXIX, R14 = aryl or alkyl) of racemate (XXXVIII) (preferably the 4-O-acetyl and 4-O-propionyl derivatives) with an appropriat...
The invention provides a commercially attractive process for the preparation of a 2,4-dideoxyhexose or a 2,4,6-trideoxyhexose by means of an enzyme catalyzed aldol condensation. This is accomplished according to the invention by carrying out the reaction between the substituted or unsubstituted ca...
usedtoremoveexcessmethano1.ThereactantwaspurifiedthroughaSep—PakC18reversalphasecolumn.Theradiochemi—calpurityandinvivostabilityweredeterminedusingsilicagelthinlayerchromatography(TLC).Thebiodjs仃ibutionofI—FIAUinKunmingmicewasalsodetected.TheresultsshowedthatI-FIAUcouldberadiolabeledefectivelywithFTAU,withmean...
Uremia is the clinical state or syndrome that is reversed by dialysis therapy, and it literally means “urine in the blood.” Whether or not urine output falls, all patients with uremia accumulate solutes, collectively known as uremic toxins. It is this accumulation of solute, the most abundant...
18F-labelled tracers for PET therefore have to be synthesised and purified as rapidly as possible, and ideally within one hour of clinical use. Standard synthetic methods for introducing fluorine-18 are relatively slow and require post-reaction purification (for example, by HPLC) which means that ...