Dengue virus has a highly ordered structure when grown in mosquito cells at 28 °C. The finding that the virus expands into a less ordered form at 37 °C indicates that the human immune system does not see it as we previously thought....
Figure 3: Dengue virus structure The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid, which is made of the viral genome and C proteins. The nucleocapsid is surrounded by a membrane called the viral envelope, a lipid bilayer that is taken from the host. Embed...
Hepatitis A Virus: Structure and Function The Reoviridae Virus Family: Structure, Transmission, and Disease Replication of RNA Viruses Lesson Plan Lassa Virus | Transmission, Diagnosis & Treatment Measles and Mumps: Disease of the Paramyxoviridae Virus Family ...
The first structure of a flavivirus has been determined by using a combination of cryoelectron microscopy and fitting of the known structure of glycoprotein E into the electron density map. The virus core, within a lipid bilayer, has a less-ordered structure than the external, icosahedral scaffol...
Structure and Functional Studies on Dengue-2 Virus GenomeClonesDengueDeoxyribonucleic acidsMolecular structureAmino acidsAntigensComputer programsHybridizationNucleotidesPeptidesOut of eleven cDNA clones, we selected three for further characterization by DNA sequence analysis. Two of these clones overlapped by ...
Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell. 2002; 108(5):717–25. 10. Byk LA, Gamarnik AV. Properties and Functions of the Dengue Virus Capsid Protein. Annu Rev Virol. 2016;3(1):263–81. 11. Christian EA, Kahle KM, Mattia K, ...
Dengue virus has two membrane proteins, E and M, which undergo dramatic structural changes during the life cycle of the virus. The 3.5-Å cryo-EM structure of the mature prefusion Dengue virion reveals the detailed interactions between E and M, providi
The class II fusion (E) protein ofdengue virushas a distinctly different structure to the class I fusion protein of thehaemagglutininof influenza virus. In common with the E protein of tick-borne encephalitis virus, the dengue E protein is ordered as 90 dimers flat-packed on the surface of ...
positioning itself upstream of the conserved 3’ stem-loop structure near the two dumbbell structures. The PABP-interacting protein 2 (PAIP2), a translation inhibitor specific to PABP, plays a role in interfering with the interaction between the Dengue virus 3’ UTR and PABP.In-vitroexperiments...
Dengue virus non-structural 1(DENV NS1)protein plays a critical role in viral pathogenesis and protective immunity.Therefore,immunity to Dengue 1-4NS1 subtypes may be crucial for the prevention of severe disease.This review attempts to provide an overview about the structure and function of DENV ...