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Malaysia continues to record high number of dengue cases despite efforts to reduce dengue transmission by vector control. Hence, safe and efficient vaccine is essential to effective dengue control. To vaccinate a significant proportion of the population, the vaccine must be affordable. This paper ...
In Malaysia, dengue vaccine intention was influenced by perceived health benefits, positive attitudes toward advancements in science and technology, and trust in public health officials [37]. However, vaccine intention can change rapidly after external events; for example, vaccine coverage in the ...
Vaccine 33, 7061–7068 (2015). Article CAS PubMed Google Scholar Srikiatkhachorn, A. et al. Dengue hemorrhagic fever: the sensitivity and specificity of the world health organization definition for identification of severe cases of dengue in Thailand, 1994–2005. Clin. Infect. Dis. 50, ...
This vaccine underwent placebo-controlled clinical studies in 35,000 children, aged 2–16 years in ten dengue-endemic countries to assess its effectiveness and safety. However, the efficacy of the vaccine was not conclusive [8]. Dengvaxia is one such promising vaccine; however, with low efficacy...
Centre for Virus and Vaccine Research, Sunway University, 5, Jalan Universiti, 47500, Bandar Sunway, Selangor, Malaysia Mohd Ishtiaq Anasir & Chit Laa Poh Contributions MIA wrote the manuscript. CLP provided the critical revision and final approval of the manuscript. ...
A licensed dengue vaccine, Dengvaxia10, has recently become available in the absence of an antiviral cure, but still, it falls short in protection due to its partial efficacy and safety issues11. Therefore, vector surveillance remains the critical core of the dengue control program in ...
BMC Infectious Diseases (2019) 19:750 https://doi.org/10.1186/s12879-019-4369-5 RESEARCH ARTICLE Systematic review of dengue vaccine efficacy Lucia Teresa Côrtes da Silveira1* , Bernardo Tura2 and Marisa Santos3 Open Access Abstract Background: Dengue is an arbovirus that has rapidly spread...
Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial. Lancet. 2014;384(9951):1358–65. Article CAS PubMed Google Scholar Wilder-Smith A. Dengue vaccine development: status and future. ...