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Three alert levels, depending on the number of cases in the cluster, lead to efforts to mobilise the community to check their prem- ises for mosquito breeding, and guide the extent of NEA's vector control intervention. However, these alert levels are based on current or recent infections, ...
Dengue virus (DENV) is a rapidly spreading mosquito-borne viral disease that is dispersed throughout the trop- ical and subtropical world1. At present, there are approximately 400 million DENV-infected patients and 2.5 billion individuals are at risk of DENV infection in the world2. DENV ...
The effectiveness of these αDENV-GrpIs to target infecting DENV genomes is also validated in transfected or transformed Aedes mosquito cell lines upon infection with unattenuated DENV-2 NGC. Conclusions Analysis shows that our αDENV-GrpIs have the ability to effectively trans-splice the DENV ...
In the natural infection, DV is introduced into human skin by an infected mosquito vector where it is believed to target immature dendritic cells (DCs) and Langerhans cells (LCs). We found that DV productively infects DCs but not LCs. We show here that the interactions between DV E protein...
However, dengue disease remains unsurpassed as the most rapidly-emerging mosquito-borne viral disease in humans [1]. Now endemic in more than 100 countries, dengue prevalence is widespread. Regions particularly affected include Southeast Asia, the Americas, and the Western Pacific, where abundant ...
viruses Article piRNA Profiling of Dengue Virus Type 2-Infected Asian Tiger Mosquito and Midgut Tissues Yanhai Wang 1,2, Binbin Jin 1, Peiwen Liu 1, Jing Li 1, Xiaoguang Chen 1 and Jinbao Gu 1,* 1 Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Pathogen ...
CHIKV is a mosquito-transmitted alphavirus that belongs to the Togaviridae family [5]. It is a reemergent arbovirus that is responsible for chikungunya fever (CHIKF), severe joint pain and rash [6]. CHIKF was first described in 1952 after an outbreak along the borders of Tanzania (former...