As one of the key neglected tropical diseases (NTDs)1,2, dengue fever is a viral infection transmitted to humans through the bite of infected mosquitoes, primarily Aedes albopictus and Aedes aegypti3. The global incidence of dengue fever has notably increased over the past two decades. According...
has recently reported a case series of dengue-associated paediatric ALF with a mortality rate of 42 % (14/33 patients died), there were several major study limitations [10]. First, the heterogeneity of the PALF population by dengue haemorrhagic fever (DHF) encompassed a vast array of disease...
protein 1 (NS1) is a highly conserved specific soluble glycoprotein that plays a role in viral replication [14] and can be detected in patients' serum up to 18 days after the onset of symptoms such as a fever [15], with a peak sensitivity in the first three days of fever [16,17]....
Ecological factors associated with dengue fever in a central highlands province, Vietnam. BMC Infect. Dis. 2011, 11, 172. [CrossRef] [PubMed] 9. Rubio-Palis, Y.; Pérez-Ybarra, L.M.; Infante-Ruíz, M.; Comach, G.; Urdaneta-Márquez, L. Influence of climatic variables on dengue ...
However, the risk of potentially life-threatening conditions, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), may be increased in regions where hyper-endemicity and co-circulation of more than one DENV serotype occur [4,6]. An estimated 500,000 people are hospitalized...