Epitope of dengue virus E protein detect human antibodies associated with mild disease: a potential peptide for vaccine development - ScienceDirectAntibodiesDengue virusEpitopesPeptidesThe antigenic potential of seven immunogenic peptides of the dengue virus was evaluated in the sera of patients with ...
The patients included in this study were enrolled at the Hospital General O’Horan Emergency Department during a two-week period in September 2015, at the height of the CHIKV outbreak in Yucatan. Patients presented fever greater than 38 °C and two or more of the following symptoms: rash, ...
Signaling of Nrf2-CLEC5A contributes to TNF-α production during DENV infection Full size image DENV NS2B3 is involved in ER stress induction, Nrf2 activation, CLEC5A upregulation and TNF-α production Full size image ATRA treatment suppresses CLEC5A expression and TNF-α production in a suckli...
DENV infection causes acute human diseases ranging from a self-limiting illness called dengue fever (DF) to a life-threatening form of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS)3. The therapeutic strategy for DENV-infected patients and the prevention of a second infection by...
Supernatants were dried and whole lipids were dissolved with chloroform/methanol/water (30:60:8, v/v/v) and then applied to a DEAE Sephadex A-25 (Sigma, St. Luis, MO, USA) on a glass column (Internal diameter×Length, 5×80 mm) for separation of neutral and acidic lipid fraction. ...
"Our first and foremost goal is to have a point of care, potentially a personal device, which is simple to use. This would allow people to detect theviruspromptly without having to go to a hospital, which would have significant impacts in developing countries," he said. "However, we're ...
Dengue viruses are the most important arboviral pathogens in the world, which have adapted to human transmission and replication over several hundred years and were initially recognized to cause outbreaks of clinical disease in tropical and subtropical c
Epitope of dengue virus E protein detect human antibodies associated with mild disease: a potential peptide for vaccine developmentdoi:10.1016/J.BJID.2019.10.009Gilma Sánchez-BurgosCarla Herrera-NájeraRoberto Cedillo-RiveraEric DumonteilBraz J Infect Dis...
Results 129 of 426 patients had ultrasonography‐confirmed plasma leakage while 146 had a haematocrit rise >20%. Those positive on ultrasonography were also likely to fulfil the haematocrit‐based criteria (OR: 4.42, 95% CI: 2.85–6.86), but the two groups did not overlap fully. In the ...
Regina Helena Saramago Peralta cJosé Mauro Peralta aJournal of Clinical VirologyCabral-Castro MJ, Cavalcanti MG, Peralta RH, Peralta JM. Molecular and serological techniques to detect co-circulation of DENV, ZIKV and CHIKV in suspected dengue-like syndrome patients. Journal of clinical virology : ...