Dementia with Lewy bodies ('Lewy body dementia' or 'diffuse Lewy body disease') (DLB) is the second commonest form of dementia after Alzheimer's disease (AD). Characteristic of DLB are: (1) fluctuating cognitive ability with variations in attention and alertness, (2) recurrent visual ...
在存在任何其他身体疾病或神经功能障碍(包括脑血管疾病)的情况下,DLB发生的可能性要小得多,足以说明部分或甚至全部的临床情况,尽管这些不排除DLB,并且可能表现出归因于临床表现的混合或多种病理;或者如果帕金森病征是唯一的基本临床症状,并且在一定程度的严重痴...
Gut microbiota and fecal bile acids were analyzed in 278 patients with α-synucleinopathies, which were comprised of 28 patients with dementia with Lewy bodies (DLB), 224 patients with Parkinson’s disease (PD), and 26 patients with idiopathic rapid eye movement sleep behavior disorder (iRBD)....
A recent study has investigated potential risk factors for dementia with Lewy bodies (DLB) in a cohort of 147 patients. Of the 19 candidate factors studied, a history of anxiety, stroke, family history of Parkinson disease (PD), and harbouring the apolipoprotein 蔚4 allele were more common ...
路易体痴呆(dementia with Lewy bodies, DLB)是最常见的神经变性病性痴呆之一,仅次于阿尔茨海默病(Alzheimer disease, AD)。除痴呆外,其特征性临床表现还包括:视幻觉、帕金森综合征、波动性认知障碍、自主神经功能障碍、睡眠障碍,以及对抗精神病药物敏感。
Dementia withLewy bodies(DLB) is a progressive disease characterized by cognitive, neuropsychiatric, autonomic, sleep, and, to a lesser extent, motor symptoms. Lewy bodies and Lewyneuritesare pathologic aggregations of alfa-synuclein. The pathologic presence of Lewy bodies occurs, as in IPD, in th...
Dementia with Lewy bodies (DLB) is an age-associated neurodegenerative disorder producing progressive cognitive decline that interferes with normal life and daily activities. Neuropathologically, DLB is characterised by the accumulation of aggregated α-synuclein protein in Lewy bodies and Lewy neurites...
Dementia with Lewy bodies (DLB) is perhaps the second most common cause of degenerative dementia after Alzheimer's disease. This book, which represents the first authoritative statement about DLB, arises from a workshop held in Newcastle, England, in October 1995, which brought together leading in...
Dementia with Lewy bodies (DLB) is a degenerative disorder characterized by progressive cognitive decline combined with three additional defining features: (1) pronounced fluctuations in alertness and attention (e.g., frequent drowsiness, lethargy, and disorganized speech), (2) visual hallucinations, an...
Dementia with Lewy bodies (DLB) has over the last two decades become recognised as a common dementia subtype in older people. Since it shares clinical and pathological features with both Alzheimer’s disease and Parkinson’s disease, knowledge of DLB is essential not only in its own right, but...