The prevalence of Parkinson's disease dementia (PDD) is roughly estimated to be around 30 %, while PDD will occur in over 80 % of patients after 20 years of disease, conferring an important impact on patient management and prognosis. The main clinical syndrome of PDD is that of a frontal...
路易体痴呆包括路易体痴呆和帕金森病痴呆,是神经退行性痴呆的第二大常见原因。包括DLB和帕金森病伴(路易体)痴呆(Parkinson disease with dementia, PDD)的总称。越来越多的共识认为DLB是一种独特的临床疾病,其特点是早发痴呆、进展更快速。相比之下,PDD患者出...
Dementia in Parkinson Disease 来自 Springer 喜欢 0 阅读量: 32 作者: AD Korczyn 摘要: The possibility that Parkinson disease is associated with dementia has been negated by neurologists for several decades. However, the story is more complex. It should be recalled that predating levodopa therapy...
Dementia can occur in a substantial number of patients with Parkinson's disease with a point prevalence close to 30%. The cognitive profile is characterized by predominant deficits in executive, visuospatial functions, attention and memory. Behavioral symptoms are frequent such as apathy, visual halluc...
Objective To identify factors associated with dementia in a cohort of Parkinson's disease (PD) brain donors and determine whether its presence may influence the clinical phenotype of the disease. Methods We included 67 consecutive patients with a clinical and pathological diagnosis of PD, who while...
包括DLB和帕金森病伴(路易体)痴呆(Parkinson disease with dementia, PDD)的总称。越来越多的共识认为DLB是一种独特的临床疾病,其特点是早发痴呆、进展更快速。相比之下,PDD患者出现痴呆的时间要晚得多,有时甚至在帕金森病(Parkinson disease, PD)发病后10年才出现。虽然这两种疾病的临床特征和病理学类似,但临床对...
The prevalence of dementia, assessed on the basis of the Wechsler scale (WAIS), was determined in a group of 88 patients with idiopathic Parkinson's disease (PD) lasting longer than 4 years. In this group, 19 patients (22%) were diagnosed as demented. They were significantly older...
帕金森病(Parkinsondisease)帕金森病的概念 •帕金森病(Parkinson’sdisease,PD)又名震颤麻痹(paralysisagitans)。•本病由Parkinson(1817)首先描述。流行病学 65岁以上人群中患病率为1700/10万，并随年龄增长而增高，两性分布差异不大；是常见的中老年人神经系统变性疾病。病因及发病机制 本病病因迄今未明-...
Spectroscopic changes associated with mild cognitive impairment and dementia in Parkinson's disease. Frontal subcortical cognitive defects are predominant in Parkinson's disease (PD). Temporal lobe dysfunction seems more relevant for progression to dementi... J Pagonabarraga,B Gómez-Ansón,R Rotger,....
Dementia in Parkinson's disease encompasses a spectrum relating to motor, psychiatric, and cognitive symptoms that are classified as either Dementia with Lewy Bodies (DLB) (initial cognitive symptoms) or Parkinson's Disease Dementia (PDD) (initial motor signs preceding cognitive symptoms by at least...