Porcine delta coronavirus (PDCoV) and porcine epidemic diarrhea (PEDv) have economically impacted the pork industry. These viruses are known to be transmitted via fecal matter and raises concerns of biosecurity. The objectives were to determine mitigation strategies to minimize or eliminate the risk ...
Porcine delta coronavirus inhibits NHE3 activity of porcine intestinal epithelial cells through miR-361–3p/NHE3 regulatory axis 来自 dx.doi.org 喜欢 0 阅读量: 2 作者:Z Huang,M Cao,H Fan,Y Sun,T Lan,J Ma,Q Li 摘要: The relevant research is reported for the first time in PDCoV, ...
Coronaviruses attach to cell surface receptors and then enter the cell by fusion at the plasma membrane or after endocytosis (Fig. 2.2, paths A2 and A1, respectively) (Perlman and Netland, 2009). Replication occurs in the cytoplasm. After uncoating, genome replication possibly occurs on double...
Advax™ adjuvant enhanced neutralizing antibody responses and protection in a murine model of severe acute respiratory syndrome (SARS) coronavirus. Formulations of either inactivated SARS virus or recombinant spike protein with Advax™ adjuvant protected mice and reduced lung virus titres when compared...
Swine acute diarrhoea syndrome coronavirus (SADS-CoV), which originates from zoonotic transmission of bat coronaviruses in the HKU2 lineage, causes severe illness in pigs and carries a high risk of spreading to humans. At present, there are no licenced therapeutics for the treatment of SADS-...
The use of cells from ANPEP knockout pigs to evaluate the role of aminopeptidase N (APN) as a receptor for porcine deltacoronavirus (PDCoV)ANPEPAPNAminopeptidase NCD13CRISPRPorcine deltacoronavirusThe coronaviruses, porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), and...