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As a result, the amount of medicine that can be delivered nasally is limited. Apart from that, large-scale manufacturing of CBS can be challenging due to its high viscosity. Furthermore, as the CBS contains a large amount of water, there is less entrapment of water-soluble components. ...
In addition, CS is only dissolved in acid solutions and has limited mucoadhesive abilities. A series of CS derivatives such as TMC, O-and N-carboxymethyl CS, N-methylene phosphonic CS, carbohydrate branched CS and alkylated CS are synthesized to solve these problems. Many researches have been ...
Hospital systems in the Covid pandemic are challenged with the dual responsibility of delivering non-Covid and Covid care. To assess the impact of Covid pandemiDuggal, BhanuDuggal, MonaChourase, MithleshGedam, PraveenSaunik, SujataSocial Science Electronic Publishing...
stabilised and consolidated to prevent reduced efficacy as well as disruption within aqueous solutions [175]. Nanofilms can be used to overcome the shortcomings of biomaterials with single layer fabrication such as hydrogels, which present disadvantages like rapid release of the integrated therapeutic agen...
Microfabrication will continue to offer new, alternative solutions for the development of smart, advanced drug delivery systems. Keywords: microfabrication; drug delivery; biocompatibility 1. Introduction Nanobiotechology represents the link between engineering and life sciences [1]. On the one hand, the...
There are also advanced solutions to this issue, such as modifying the MSC-EV surface with targeting ligands that will increase the efficiency of vesicle internalization, in contrast with the mechanisms described earlier [69]. These options would increase the specificity of the EVs while preserving ...
(ERT) lie in their ability to facilitate the transportation of a larger quantity of enzymes to the brain. Accordingly, they obviate the need for administering excessively high doses of therapeutic drugs. In addition, these proposed solutions effectively tackle the challenges related to the limited ...
Amid the rise of antibiotic-resistant bacterial strains in human populations, novel solutions are necessary. Nanoparticles, renowned for their adaptability, offer a diverse range of research avenues, notably as antibacterial agents. Coupling antibiotics with nanoparticles stands out as a potential strategy...
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