No efficient treatment exists for nephrotic syndrome (NS), a frequent cause of chronic kidney disease. Here we show mutations in six different genes (MAGI2, TNS2, DLC1, CDK20, ITSN1, ITSN2) as causing NS in 17 families with partially treatment-sensitive NS (pTSNS). These proteins interac...
Genomic insights that advance the species definition for prokaryotes Proc Natl Acad Sci U S A, 102 (2005), pp. 2567-2572 10.1073/pnas.0409727102 CrossrefView in ScopusGoogle Scholar 10. C Jain, LM Rodriguez-R, AM Phillippy, KT Konstantinidis, S Aluru High throughput ANI analysis of 90K pr...
Results for the last round of cell division were not included because, by definition, SDm-d equals SDm-t − SDd-t in these cells. Supplementary information Supplementary Information Supplementary Notes 1–6, Supplementary Figs. 1–5 and references. Reporting Summary Supplementary Table 1 ...
Secondary structures in experimentally determined protein coordinate data often deviate from the ideal geometry and thus methods of secondary structure assignment that use different logic and cutoffs can vary significantly in their assignments. Maximum variation is seen near the edges of SSEs and consensus...
The invariance properties of their mathematical definition help give anisotropy creases the attractive property of being parameter free (aside from the choice of convolution kernels), in contrast to most tractography and clustering algorithms. Future work will include extraction of FA ridge lines, and ...
(D) Genome-wide frequency (percentage of CDK12 wild-type patients) of FTDs based on a narrow (< 2Mb) and wide (< 8Mb) definition of focality. (E) Frequency of CDK12-FTDs at the most recurrent loci in CDK12 mutant and wild-type tumors. (F) Effect of CDK12-FTDs on the frequency...