Larger implants produce a proportionally higher magnitude of foreign body reaction and fibrosis. For polymers that are susceptible to autocatalysis, in addition to being dependent on flow conditions at the implantation site, there is a critical thickness at which hydrolytic degradation will be ...
The discovery of the enzyme has fueled the development of a series of molecules structurally related toFeTpiPr2acacNCMe, containing a nitrogen-based tripodal tridentate ligand and β-diketonato ligands as substrate mimics. Sign in to download full-size image Scheme 10. Reaction of [FeII(TpiPr2...
So far, only very few CBM33 and GH61 proteins have been successfully overexpressed and characterized. Moreover, characterization work has often been limited to testing only a few reaction conditions (in terms of the type of substrate, the pH of the reaction, the reaction temperature, the type ...
As HMM revealed the gene candidates with the highest potential for fucoidan degradation, we could clone, test, and characterise two active, thermostable α-L-fucosidases. These enzyme structures are most similar to an α-L-fucosidase synthesised by aBacillotaspecies. However, protein–protein blas...
The stereochemical course of this reaction was investigated through the synthesis of four stereoselectively deuterated substrate surrogates carrying stereoselective deuterations at the alpha- or the beta-carbon. Analysis of the products revealed a specific abstraction of the 2-pro-R ...
In order to compare the catalase-activity of AuNPs with that of catalase enzyme, we determined turnover frequency of Au@PVPs by plotting reaction rate vs Au@PVP concentration data (Supplementary Infor mation Fig. S4). When turnover frequency is defined by number of hydrogen peroxide ...
Enzyme mediated decolorization is another newer alternative, where the enzyme can specifically react with organic pollutants by transforming them into low molecular weight products[23]. The main advantage of using enzymes in degrading dye solutions is that they have higher reaction rates and can also ...
nucleophile to attack the carbonyl carbon (C) of the substrate to afford an acyl-enzyme intermediate. Then, the R2group is removed from the polymer in an alcohol form due to an elimination reaction. The acyl-enzyme intermediate is then attacked by a water molecule (H2O) to afford the acid...
An assay using 8−14C−i6A as substrate was used to assay various tissues for this enzyme activity. The major site of occurrence of this enzyme is associated with the blood system. The enzyme activity was detected in chicken, pig, rabbit, and human samples. An assay based on gas chro...
(k∗) and the half-lives of the acting enzyme. One must note that the assumption of bulk degradation will not hold at highenzyme concentrations(i.e., high reaction rates) or in thick gels where the diffusion timescale is large. Under these conditions significant surface erosion will occur...