Degenerative Disease The term degeneration is commonly applied to morphology reflective of an aging spine. Areas of increased axial loading may cause arthritic changes at joint and disc spaces, most commonly seen at C5-6 and C6-7 or L4-5 and L5-S1 in the cervical and lumbar spine, respective...
However, noncontinuous ACDF would increase degenerative risks at adjacent and intermediate levels. In addition, the application of Prodisc-C in noncontinuous CAD may have more advantages than that of Prestige LP.Introduction Noncontiguous cervical degenerative disc disease (CDDD) is defined as cervical...
degenerationand much effort has been placed into correlating MRI findings with potentially symptomatic levels. In the right hands, a provocative test,discography, can be used to correlate clinical symptoms with the MRI appearance. Although each finding of degenerative disc disease will be discussed ...
Degenerative cervical myelopathy (DCM) is a disease concept that includes age-related degenerative changes of the cervical spine, such as intervertebral disc disease, vertebral remodeling, hypertrophy and/or ossification of spinal ligaments, and spondylolisthesis. Cervical spondylolisthesis prevalence has been...
partial assistance. Four months after surgery, the C4 and C5 spacers were dislocated; however, because her symptoms had not worsened, no additional surgery was performed. At the final follow-up 4.5 years after surgery, the limb numbness had not worsened and the JOA score was 7.5 (Figure 2)...
Degenerative disc disease with disc space narrowing and anterior osteophyte formation at C5-6 (arrow). Full size image Figure 3 Severe facet arthrosis affecting C3-6 bilaterally (arrows). Full size image The presence of osteoarthrosis is often confirmed using plain film radiographic findings, with ...
spinal surgery not related to degenerative disc disease or significant metabolic processes, such as ochondrosis or mucoplysaccharidoses. All elements of the spine, including the intervertebral discs, joints, ligaments and bony structures, may undergo morphological changes that can be classified as dege...
A composition comprising mesenchymal stem cells, or AgRP or an active fragment thereof according to one aspect has the effect of being useful for preventing, treating, or alleviating a disease associated with decrease activity of ubiquitin proteasome, for example, a degenerative brain disease by ...
Clinical nomograms, such as PSA levels and Gleason score, can be used to identify patients at high risk of metastatic disease at presentation.29,30 For preoperative management, BS is not required in asymptomatic patients or where serum PSA levels are <10 ng/mL. However, in symptomatic ...
In this study, the cell senescence phenotype was found to be more prominent in the CEP cells obtained from disc degenerative disease (DDD) patients than in the CEP cells obtained from age-matched lumbar vertebral fractures (LVF) patients. In addition, the results indicated that p53/p21 pathway...