产品名称:Anti-H_CCR8 hIgG1 Antibody(Defucosylated,BMS-986340) 目录价:询价规格货号 GM-53822AB-100 100 μg GM-53822AB-1000 1 mg产品简介 Species Reactivity Human Clone Defucosylated,BMS-986340 Source/Isotype Monoclonal Human IgG1 Application Flow Cytometry; Bioassay Specificity Detects CCR8 Gene ...
2009. Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model. Cancer Immunol. Immunother. 58: 1195-1206.Ito A, Ishida T, Yano H, Inagaki A, Suzuki S, Sato F, Takino H, ...
In this model, the chimeric anti-CCR4 monoclonal antibody (mAb), KM2760, the Fc region of which is defucosylated to highly enhance ADCC, showed potent antitumor activity by human ADCC against CCR4 expressing tumor cell lines. In addition, KM2760 significantly increased the number of tumor-...
This phase 1/2 study evaluated the efficacy of mogamulizumab, a defucosylated, humanized, anti-CC chemokine receptor 4 monoclonal antibody, in 41 pretreated patients with cutaneous T-cell lymphoma. No dose-limiting toxicity was observed and the maximum tolerated dose was not reached in phase 1...
Depolymerized holothurian glycosaminoglycan (DHG) is a fucosylated chrondroitin sulfate that possesses antithrombin-independent antithrombotic properties a... JP Sheehan,EN Walke - 《Blood》 被引量: 94发表: 2006年 DEPOLYMERIZED FUCOSYLATED GLYCOSAMINOGLYCAN AND PREPARATION METHOD THEREOF Disclosed is a met...
Human milk is rich in fucosylated oligosaccharides and other glycoconjugates, some of which affect interactions between pathogens and host cell surface. Tw... GY Wiederschain,DS Newburg - 《Journal of Nutritional Biochemistry》 被引量: 33发表: 1995年 An α-L-fucosidase from Thermus sp. with ...
Besuchen Sie ChemicalBook finden Sie mehr Monogalactosylated fucosylated asialo, agalacto, biantennary (G-NGA2F) Informationen wie chemische Eigenschaften, Struktur, Schmelzpunkt, Siedepunkt, Dichte, Summenformel, Molekulargewicht, physikalische Eigensch
Besuchen Sie ChemicalBook finden Sie mehr ASIALO, GALACTOSYLATED, FUCOSYLATED BIANTENNARY Informationen wie chemische Eigenschaften, Struktur, Schmelzpunkt, Siedepunkt, Dichte, Summenformel, Molekulargewicht, physikalische Eigenschaften, Toxizität Inf
Because L Mab-13 lacks antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), we first converted the subclass of L Mab-13 from IgG into IgG (13-mG ), and further produced a defucosylated version (13-mG -f) using FUT8-deficient ExpiCHO-S (BINDS-09) ...
Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor 来自 ACS 喜欢 0 阅读量: 48 作者: K Hiruma-Shimizu,K Hosoguchi,Y Liu,N Fujitani,T Ohta,H Hinou,T Matsushita,H Shimizu,T Feizi,SI Nishimura 展开 ...