The mechanisms of drug hypersensitivity are not well understood. This is reflected by difficulties in their classification, which is mainly based upon the current knowledge of immunologic and nonimmunologic mechanisms, onset of symptoms (immediate or nonimmediate) and morphology. For the individual ...
Each generation of offspring has increased severity of a genetic disorder; e.g., a grandchild may have earlier onset and more severe symptoms than the parent, who had earlier onset than the grandparent. See also: additive genetic effects, complex trait Antisense Nucleic acid that has a se...
disease pattern did not live significantly longer than non-tremor dominant patients and showed no difference in mean time to onset of falls and ... M Selikhova,DR Williams,PA Kempster,... - 《Brain A Journal of Neurology》 被引量: 522发表: 2009年 Classification of movement disorders. tremor...
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and
Each generation of offspring has increased severity of a genetic disorder; e.g., a grandchild may have earlier onset and more severe symptoms than the parent, who had earlier onset than the grandparent. See also: additive genetic effects, complex trait Antisense Nucleic acid that has a se...
The article focuses on the paper released by James Seddon of the Desmond Tutu TB Centre and colleagues on The Sentinel Project concerning definitions used for adults with drug-resistant tuberculosis (TB) and for children with drug-susceptible TB, published in a 2013 issue of the "Journal of Ped...
This generally involves use of several drugs with selective and complementary actions. The pharmacokinetic properties of such drugs should allow rapid onset, rapid recovery, and rapid responses to changes in delivered doses. Peri-operative management issues also are inherent to use of modern drugs ...
The baseline SOFA score should be assumed to be zero unless the patient is known to have preexisting (acute or chronic) organ dysfunction before the onset of infection. Patients with a SOFA score of 2 or more had an overall mortality risk of approximately 10% in a general hospital ...
High school students are having less sexual intercourse. That’s what the studies say. But that doesn’t mean they’re having less sex. The language of young love and lust, and the actions behind it, are evolving. And experts say the shift is not being a
The researchers noted variation with respect to timing sincesymptom onsetand minimum duration required for diagnosis in five clinical definitions of long COVID; one additional definition was based on symptom scores. Five key principles informed 49 long COVID care models: a core "lead" team, multidi...