Related to frameshift mutation:point mutation,missense mutation frame·shift mutation (frām′shĭft′) n. A mutation in a DNA chain that occurs when the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is rea...
frameshift mutagenframe·shift mu·ta·gen a mutagen, such as an acridine derivative, that causes a reading-frame-shift mutation; codons (base triplets) are read out of phase and different amino acids are used. Farlex Partner Medical Dictionary © Farlex 2012...
The meaning of FRAMESHIFT is relating to, being, or causing a mutation in which a number of nucleotides not divisible by three is inserted or deleted so as to change the reading frame of some triplet codons during genetic translation. How to use frameshi
if amutation, for example, an insertion or a deletion of the nucleotide, occurs, this could result in the alteration of the reading frame. It completely changes the amino acid sequence. Such mutations are known as frameshift mutation (also calledreading frame mutation, reading frame shift,orfram...
Frameshift mutation definition A frameshift mutation is a type of genetic mutation resulting from the alteration of a number of nucleotides in DNA sequences that are not multiple of three. Frameshift mutation occurs as a result of a change in the reading frame of the sequence. Since the codons...
The meaning of MUTATION is a significant and basic alteration : change. How to use mutation in a sentence.
Silent mutation A frameshift mutation is a type of gene mutation wherein the addition or deletion of (a number of) nucleotide(s) causes a shift in the reading frame of the codons in the mRNA. This leads to the alteration in the sequence of amino acids during protein translation. A nonsens...
Insertional mutations are a type of frameshift mutation. In a frameshift mutation, all of the codons downstream from the mutation are changed, which generally produces significant changes in the protein. This is because inserting a new nucleotide shifts the reading frame for all codons after it. ...
point mutation substitution during replication, one base is inserted incorrectly, replacing the pair at the appropriate location on the complementary strand. sickle-cell anemia insertion in replicating dna, one or more additional nucleotides are added, frequently causing a frameshift. one form of beta-...
Two of these alleles, however, are extinct and unavailable for further analysis. In this article we report a new spontaneous dr allele and describe the Lmx1a mutations in this and six additional dr alleles. Strikingly, deletion null, missense, and frameshift mutations in these alleles all cause...