There is much evidence for the need of well-defined and structured functional descriptions [1–4]. However, the main difficulty encountered is that 'function' is not a well defined concept and it is not as un-e
A common feature of these different approaches is that they rely mainly on the semantic links of the DAG. Unfortunately, there are inherent problems in this approach due to the non-homogeneity and the uneven distribution of the biological knowledge. As a result some regions of the DAG are more...