Vulnerable populationsEthicsClinical trialsIn this study, we interviewed researchers, asking them to define vulnerable populations in HIV/AIDS clinical trials, and provide feedback on the federal regulations for
In research ethics, Indigenous peoples used to be labelled as a vulnerable group. For instance, the 2012 UNAIDS Ethical Considerations in Biomedical HIV Prevention Trials noted: Examples of populations that may have an increased vulnerability include women, children and adolescents, men who have sex ...
and automotive. Workers in such exposed sectors are especially vulnerable; for example, by 2050 in the Net Zero 2050 scenario, demand for fossil fuel–based power jobs could be about 60 percent lower compared to today’s direct jobs related to operational activities due to the net-zero t...
The cities are made up of diverse populations covering different socioeconomic statuses that each have different needs. Recognizing and embracing such differences can prevent divisive strategies that negatively impact a city, such as only implementing innovations in wealthy neighborhoods or installing ...
Despite being a relatively low transmission area, the complexities of multi-drug-resistant malaria and the movement of vulnerable populations require an approach that is not only technically sound, but simple enough to be achievable. Trial registration ClinicalTrials.gov, ID: NCT02653898. Registered ...
Although HCC1806 cells harbors high cyclin E1 levels, they are not vulnerable to the loss of CCNE1, which makes this model distinct from MB157. Co-immunoprecipitation revealed that the depletion of cyclin E1 results in the formation of cyclin D1/CDK4 complex, which could impart resistance to...
As a result, small and fragmented wildlife populations are more vulnerable to genetic drift and inbreeding3, which, in turn may reduce their fitness and evolutionary potential, eventually driving species to extinction4. In such populations it is particularly important to thoroughly understand basic ...
[4,7].Women alsotendtolivelongerthanmen,sotheyconstitutealarge shareofthevulnerablepopulation.Positiveassociationswere found between accessibility of facilities, housing density, populationdensity,andthelevelofwalkinginseveralstudies thatfocusedonolderpopulations[8–12],andparticularly amongolderwomen[13,14]...
The underrepresentation of Asian teachers also exists in regions where Asian American populations form sizable minorities, such as the US Pacific and northeastern coasts. In New York City, the site of the current study, Asians comprise 16% of public school students, but only 6% of teachers (Dis...
In addition, they propose an approach that is especially appropriate in the context of the Green Deal. First, the Green Deal's ambition to "leave no one behind" advocates for a just and inclusive transition includ- ing for those "most vulnerable and the more exposed to harmful effects of ...