a, UMAP plots of benign breast epithelial cells and BC cells for all snRNA (left) and snATAC (right) samples. Tumor cells colored by PAM50 subtype.b, Heatmap of top 15 DEGs in snRNA-seq data from benign breast duct cells. A subset of genes from each benign cell type is highlighted ...
Scientific Reports volume 14, Article number: 29047 (2024) Cite this article 1159 Accesses Metrics details Abstract Prostate adenocarcinoma (PRAD) persists as the predominant non-cutaneous malignancy diagnosed in males, which is a primary contributor to cancer-related mortality globally. It is reported...
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60 (44%) were predicted to be secreted and 27 (20%) had no annotations. Similar proportions were observed within the 99 SSDA proteins with increased abundance in AVR aphids, with 33 (33%) and 18 (18%) proteins having a secretion signal or no annotations, respectively. These proportions of...
The Nakaseomyces clade is formed by at least nine described species among which three can be pathogenic to humans, namely Nakaseomyces glabratus (Candida glabrata), the second most-common cause of candidiasis worldwide, and two rarer emerging pathogens:
Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancerArticle Open access Published: 20 June 2022 Volume 54, pages 985–995, (2022) Cite this article Download PDF You have full access to this open access ...
Two bodies of the same volume but of different masses are in equilibrium on a lever. Will the equilibrium be violated if the lever is immersed in water so that the bodies are completely submerged? View Solution The following figure shows the use of a lever. (i) Give an example of this...
Cell viability is generally reduced by freeze-thawing in any cell type. Water influx into cells is one of the main factors for cryoinjury. Cryoprotectants accelerate water loss; however, excessive water loss causes shrinkage of cells below a lethal minimum volume [30]. The water permeability of...
Nature Medicine volume 29, pages 1979–1988 (2023)Cite this article 29k Accesses 46 Citations 118 Altmetric Metrics details Abstract Alzheimer’s disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes—aggregation of the amyloid-β (Aβ) pept...
Andersen (Life Science Editors) for comments on the manuscript; the staff at the IMP/IMBA in-house FACS facility, in particular G. Schmauss, and staff at the Molecular Biology Service. Deep sequencing was performed at the Vienna BioCenter Core Facilities. V.H. is supported by the Human ...