Define the processes of transcription and translation with examples.Question:Define the processes of transcription and translation with examples.Central dogma:The central dogma in molecular biology relates to the process of synthesising proteins. This process consists of DNA transcription and mRNA tran...
1. What is transcription? 2. What is translation? How does transcription occur, and what are its steps and directionality? What is the differences between translation and transcription in biology? Describe the role of each of the following in transcription: a. Promoter b. Transcription Factors c...
Chromatin plays a central role in eukaryotic gene regulation. We performed genome-wide mapping of epigenetically marked nucleosomes to determine their position both near transcription start sites and at distal regulatory elements, including enhancers. In prostate cancer cells, where androgen receptor binds...
Methods in Molecular BiologyWehner, N., Herfert, J., Droge-Laser, W., and Weiste, C. (2017). High-throughput protoplast trans-activation (PTA) screening to define transcription factors in auxin-mediated gene regulation. Methods Mol. Biol. 1569, 187-202. doi: 10.1007/978-1-4939-6831-2...
miR156-Regulated SPL Transcription Factors Define an Endogenous Flowering Pathway in Arabidopsis thaliana Summary The FT gene integrates several external and endogenous cues controlling flowering, including information on day length. A complex of the mobile FT ... Jia-Wei,Wang,and,... - 《Cell》 ...
TCF25, which acts as a transcriptional repressor in cell death control, has been proven to repress the transcription of the serum response factor (SRF). Overexpression of TCF25 may aggravate intestinal ulceration by depleting re-epithelialization and regeneration of submucosal smooth muscular cells ...
We obtained high-quality single-cell chromatin accessibility profiles for 447,829 cells from 80 samples, with a mean transcription start site (TSS) enrichment of ~8 for most samples (Extended Data Fig. 1a). After removing low-quality snRNA-seq cells and samples, we obtained single-cell ...
22. The ETS-domain transcription factor (TF) ELF5 is a key determinant of luminal cell fate and the secretory sublineage of luminal cells23,24. Basal breast cells, on the other hand, maintain a more mesenchymal state, with p63 and SOX family TFs playing key roles in the maintenance of ...
IkappaB alpha retains the transcription factor NF-kappaB in the cytoplasm, thus inhibiting its function. Various stimuli inactivate IkappaB alpha by trigge... K,Brown,G,... - 《Mol.cell.biol》 被引量: 27发表: 1997年 Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predi...
It has been proposed that the formation of new cell type identity requires the evolution of a unique cell type regulatory signature that includes a cell type-specific core regulatory complex (CoRC) of transcription factors, which defines the identity and coordinated gene expression pattern of the ...