A substantial minority struggled to identify signs thata person might be a survivor of human trafficking and methods for intervention.Having received training and receiving information on trafficking from an officialsource significantly increased officers' knowledge base. These results stronglysupport the ...
regulations do not safeguard children overseas who are being illegally obtained for adoption purposes without knowledge of their parents. It also reports that "human trafficking" label would opens up more legislation under which the U.S. can properly prosecute violators and others who are involved ...
(a) to develop each human being’s creative potential for the full exercise of his or her personality and citizenship; (b) to develop a new political culture grounded in proactive participation and action to strengthen the power of the people; (c) to develop individuals on the basis of a ...
To ensure that each trafficking vesicle is targeted to the correct compartment, unique identifiers (molecular “zip-codes”) are incorporated into vesicles as they bud off a donor organelle. Three types of macromolecules have emerged as major zip code candidates. They include (i) small GTPases ...
Characterization of a human homologue of the murine peripheral lymph node homing receptor. Lymphocyte trafficking is a fundamental aspect of the immune system that allows B and T lymphocytes with diverse antigen recognition specificities to be ex... Bowen,B. R - 《Journal of Cell Biology》 被引...
the LRRK2 kinase activity assessed by phosphorylation of its substrates, the Rab proteins17. Rab proteins are the main regulators of important aspects of autophagy and lysosome activity, including membrane trafficking, vesicle formation, vesicle movement along actin and tubulin networks, and membrane ...
However, relative to normal-matched tissue, the percentage of cases with higher membranous DDR1 expression was significantly lower in high vs. low GS cancers. Although nuclear localization of DDR1 was consistently detected in our tissue samples and also in cultured human PCa and normal prostate-...
The quantification of these immune cell populations can be used to predict patient response to the current anti-PD-1-based therapies, while identifying the group of patients in need of other therapeutic strategies. We also find that non-responders to monotherapy often express alternate immune ...
the LRRK2 kinase activity assessed by phosphorylation of its substrates, the Rab proteins17. Rab proteins are the main regulators of important aspects of autophagy and lysosome activity, including membrane trafficking, vesicle formation, vesicle movement along actin and tubulin networks, and membrane ...
The amazing structural variety of cells is matched only by their functional diversity, and reflects the complex interplay between biochemical and mechanical regulation. How both regulatory layers generate specifically shaped cellular domains is not fully