Make the Definition Evaluative The idea of a "problem" usually means that people think there is something wrong with the world, but wrong is a debatable term. Even if everyone accepts the same facts, not everyone will agree that the facts you (or others) have defined as a prob- lem ...
The restricted cubic spline transformation decomposes EYO into one linear term and one cubic term, which ensures the resulting fitted curve is smooth and continuous at each quantile segment. We used a Bayesian framework to analyze the relationship between biomarkers and the independent variables and ...
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[64]). It seems obvious that there is a solution to the question of whether a single analogue is within the domain of another molecule, without making prior assumptions of what is acceptable in term of differences. It is highly likely that mechanistic similarity is a pre-requisite for ...
A strong digital agenda can drive long-term value creation and boost efficiency within the PE complex. About this article Richard Bulkley EY-Parthenon Partner, Transaction Strategy and Execution, Ernst & Young LLP Leading digital value creation. Helping companies and people realize their f...
Drug resistance is a principal limitation to the long-term efficacy of cancer therapies. Cancer genome sequencing can retrospectively delineate the genetic basis of drug resistance, but this requires large numbers of post-treatment samples to nominate ca
The frequently used term “predict the prognosis” in many biomarker studies may confuse readers of the accurate definition for these two types of biomarkers. Specifically, a predictive biomarker differentiates treatment-specific survival benefits in biomarker-positive or biomarker-negative patients20and ...
Recursive prediction for long term time series forecasting using advanced models. Neurocomputing 2007, 70, 2870–2880. [CrossRef] 29. Chang, C.C.; Lin, C.J. LIBSVM: A Library for Support Vector Machines. 2001. Available online: http://www.csie.ntu.edu.tw/~cjlin/libsvm (accessed on ...
A strong digital agenda can drive long-term value creation and boost efficiency within the PE complex. About this article Richard Bulkley EY-Parthenon Partner, Transaction Strategy and Execution, Ernst & Young LLP Leading digital value creation. Helping companies and people realize their fu...
Drug resistance is a principal limitation to the long-term efficacy of cancer therapies. Cancer genome sequencing can retrospectively delineate the genetic basis of drug resistance, but this requires large numbers of post-treatment samples to nominate causal variants. Here we prospectively identify geneti...