Define correction factor What does unit mean in measurement? What are confounding variables? Define experimental group What are some weaknesses of quantitative research? What are some examples of qualitative observations? Pure science is best defined as what?
Despite the clear importance of KLF4 in promoting metastasis in our models, therapeutic inhibitors of this factor have not yet been developed. However, other in vivo dependencies from our screen, such as STAT3, have chemical probes that can be used to impair their function. We thus sought to ...
This dietary shift is a major contributory factor to the remarkable difference in T2D rate between two genetically homogeneous Pima communities [97]. In 1979, T2D was more common in first generation Japanese migrants on the island of Hawaii (mainly from Hiroshima) than in the Japanese population ...
Agonist-dependent SARS-CoV-2 sgRNA expression was investigated using agents associated with COVID-19 severity and outcome, i.e., insulin and interferon (IFN)-γ. Elevated serum insulin is a pathological hallmark of obesity24,25, a major risk factor for severe COVID-1926,27. Moreover, insulin...
22. The ETS-domain transcription factor (TF) ELF5 is a key determinant of luminal cell fate and the secretory sublineage of luminal cells23,24. Basal breast cells, on the other hand, maintain a more mesenchymal state, with p63 and SOX family TFs playing key roles in the maintenance of ...
(Fig.3e). These three proteins might give important insights into possible disease progression, especially when considering the possible confounding factor by age (Table1). For LRRK2 PD vs. iPD, HSPA1A, HSPA1B, ECM1, GBA, NEDD4L, and GDPD3 were upregulated (Fig.3b). Through microarray...
For example, a factor directly related to ice crystal formation is proposed as the physical distance of the gap junction between cell membranes [58]. To understand the freeze–thaw tolerance of cells, it is necessary to analyze the molecular mechanisms as well as the biophysics of cells. ...
Differences in TK parameters such as bioavailability or accumulation may be accommodated if sufficiently understood, by adjusting the read-across value or using a safety factor Metabolism: Metabolite identity, rate or extent of metabolism Experimentally determined metabolites, metabolites predicted using softw...
(Fig.3e). These three proteins might give important insights into possible disease progression, especially when considering the possible confounding factor by age (Table1). For LRRK2 PD vs. iPD, HSPA1A, HSPA1B, ECM1, GBA, NEDD4L, and GDPD3 were upregulated (Fig.3b). Through microarray...
Glia maturation factor beta is involved in the stimulation of neural regeneration36. Phosphatidylethanolamine-binding protein 1 is a negative regulator of the mitogen-activated protein kinase (MAPK) cascade and is also involved in the proper function of presynaptic cholinergic neurons in the central ...