specifically the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), which approximate the BC molecular subtypes2. Breast ductal epithelium, from which BC arises, is divided into...
CD56+ NK cells also remained below 10th centile in the majority of patients throughout the duration of therapy (Fig. 5D). CD19+ B cells were even more strikingly affected with median absolute counts of <50 cells/μL at all time points after diagnosis (Fig. 5E). Therefore, despite ...
Eye (2017) 31, 1594–1599; doi:10.1038/eye.2017.111; published online 16 June 2017 Introduction Diabetic macular edema (DME) is the most common cause of moderate visual impairment in patients with diabetic retinopathy and its prevalence varies from 0 to 3% in patients with recent diagnosis of ...
Suppose, after all, that the causal diagnosis is mistaken or misleading—for example, that states' unwillingness to enforce engine maintenance routines is not in fact a very important cause of air pollution. Because the term definition in some contexts connotes legitimate arbitrariness ("I'll ...
The objective of this study was to compare CXR with Computer Aided Diagnosis (CAD) against symptom screen for defining presumptive TB and how TB detection changes with each method. Household contacts of consecutive index bacteriologically confirmed TB cases were visited by study teams and given TB/...
The diagnosis of autism was made using the standard Autism Diagnostic Interview-Revised (ADI-R) [127] with three affected status categories based on ADI-R results: autism, not quite autism (NQA) and broad spectrum. In the current report, we fused the last two categories as PDD-NOS. To me...
The diagnosis of autism was made using the standard Autism Diagnostic Interview-Revised (ADI-R) [127] with three affected status categories based on ADI-R results: autism, not quite autism (NQA) and broad spectrum. In the current report, we fused the last two categories as PDD-NOS. To me...
Editor’s Choice-Is the pre-hospital ECG after out-of-hospital cardiac arrest accurate for the diagnosis of ST-elevation myocardial infarction? Background: Current guidelines recommend that comatose out-of-hospital cardiac arrest patients with ST-segment elevations (STEs) following return of sponta....
(no metastasis: median RFS 202 vs not reached, metastasis: 13 vs 27 months, p = 0.031). In multivariate Cox proportional hazards regression, the miRNA signatures remained independently prognostic of RFS when controlled for the presence of metastatic disease at diagnosis and pathologic necrosis ...
Rule 10 – Focus on Judgment and accountability: Humanity has reached a level where it can gladly accept a computer-generated diagnosis or legal decision. However, we still expect a human to be ultimately accountable for the outcomes. Transformations in rules governing AI, over time Isaac ...