O. (2012). The missing link: do cortical microtubules define plasma membrane nanodomains that modulate cellulose biosynthesis? Protoplasma 249, S59-S67. doi: 10.1007/s00709-011-0332-zFujita M, Lechner B, Barton DA, Overall RL, Wasteneys GO (2012) The missing link: do cortical microtubules...
Lees, J. A. et al. Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion.Science355, eaah6171 (2017).This manuscript showes a role for contact sites in physiology of a tissue. ArticlePubMedPubMed CentralCASGoogle Scholar Carrasco, S. & Meyer, T. ...
To quantify cellular traits, we adopted the Cell Painting assay17,18. This multiplexing dye assay uses six stains to capture morphological characteristics for eight cellular compartments: Hoechst 33342 (DNA), wheat germ agglutinin (WGA) (golgi and plasma membrane), concanavalin A (endoplasmic reticulu...
The M42 matrisome class of proteins, of which Aβ is a member, may not only contain promising AD biomarkers, but also represent promising new therapeutic targets for the disease. M42 proteins may mediate the pathologic effects of Aβ plaques through either gain or loss of function as a conseq...
Karyoplasma (n.) The protoplasmic substance of the nucleus of a cell: nucleoplasm; -- in opposition to kytoplasma, the protoplasm of the cell. Karyostenosis (n.) Direct cell division (in which there is first a simple division of the nucleus, without any changes in its structure, followed...
One such class of compartments is the set of plasmalemmal microdomains known as caveolae (1, 2). These “little caves” are 50–100 nm invaginations of the plasma membrane that have distinct morphological and biochemical properties (3, 4). Caveolae are present to some degree in most cell ...
Extracellular vesicles (EVs) are a heterogeneous array of 40- to 1000-nm diameter plasma-membrane enclosed particles that are released by all cells and have recently been described as agents of intercellular communication, capable of modifying cells within their microenvironment (Mathivanan et al., ...
In resting leukocytes, this domain is contiguous with the rest of the molecule and is expressed in the cytoplasm adjacent to the plasma membrane. However, during leukocyte activation, the C-terminus is cleaved away from the rest of sialophorin and translocates to the nucleus where it protects ...
order Coriobacteriales and class Coriobacteriia (Additional file5: Table S2). We suggest that these taxa may be considered as biomarkers for OMS. In this regard, it was recently reported that an altered abundance ofCollinsellagenus changes the host’s plasma cholesterol levels, showing a positiv...
The ESCRT machinery not only mediates the formation of MVEs, but is also involved in many other cellular membrane deformation and scission events, such as cytokinetic abscission, virus budding, plasma membrane repair and nuclear envelope reformation and repair (summarized in refs. 9,10,11). All...