Understanding your TAM, SAM and SOM means your SaaS company can find the path of least resistance to win and retain your customers by servicing them well. In the end, you might only find one part of the market that passes this test. ...
So I'm going to propose something here that may seem radical to some, but it's not really in 2022, and I believe it's "the path of least resistance" here. Let me know if you guys agree but I view three.js as serving two use cases, as a three.js "application", and as a thr...
This option provides the path of least resistance to use a database as the source of truth. Although not perfect, it should provide us (or be able to be extended) with what we need. Such should be true not just for online garbage collection, but also to migrate all API operations and...
Our results provide compelling evi- dence for the preferential utilization of either signaling com- ponent by particular R genes and thus define at least two disease resistance pathways. The data also suggest that strong dependence on EDSI or NDRI is governed by R protein structural type rather ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer genomic RNA, all bearing identical termini with poorly understood roles in regulating
Part I • The Eightfold Path 3 simplest formulation, market failure occurs when the technical properties of a good or service have one of the following effects: • Making it hard to collect payment from all the potential beneficiaries—for instance, the large number of ...
The morphology of cells is dynamic and mediated by genetic and environmental factors. Characterizing how genetic variation impacts cell morphology can provide an important link between disease association and cellular function. Here, we combine genomic s
STAT3 inhibitors, or drugs that are targeting this pathway, should not be used if the corresponding tumor does not express this tyrosine phosphorylated form of the oncogene. In addition, since STAT3 is known to play an important role in drug resistance,24 one can spec...
ABCC2, a multidrug resistance-associated protein, transports phytochelatin- (PC) arsenic complexes into the vacuoles of rice [16], barley [17], and Arabidopsis thaliana [18]. The remaining transporters, ORGANIC CATION TRANSPORTER 4 (PvOCT4), OLIGOPEPTIDE TRANSPORTER 5 (PvOPT5), and VACUOLAR ...
It’s the giddy, fun-loving flipside to the forcefulness of “We Are the Champions,” and though it similarly acknowledges outside resistance, it does so with a flick of the wrist from a shy guy still hiding behind the sybarite self he strutted onstage so legendarily. In the early ...