Branching (i.e.ifstatements for you non-assembly people) can be a real performance killer. Only do branching if you need to for the correctness of an algorithm, or to save time on an expensive computation (e.g. checking a cache). ...
The sequences corresponding to the differentially abundant transcripts identified with DESeq were used for homology search against NCBI’s NT database using the blastn algorithm from the BLAST + suite v 2.10 using with expected value 0.0001, id = 0.80, coverage 75%, Match/Mismatch 2,...
Given that CDKL5 is a protein kinase known to regulate signal transduction pathways,13,22,23,24,25,26 multiple therapeutic attempts to target protein replacement or CDKL5-dependent signaling pathways have been conducted, demonstrating encouraging phenotypic amelioration in CDD mouse models.17,27,28,29...
A comprehensive non-invasive stress-based algorithm have should be feasible, safe, simple, and prognostically relevant, thereby leading to “replace, reduce, and refine” (the 3 R’s approach) the current criteria: Replace invasive with noninvasive, ionizing with nonionizing, and rest with ...