Nonetheless, detecting admixture signals between subspecies sharing a very recent common ancestry is often hampered by the difficulty toa prioriidentify pure individuals24,26and a number of pitfalls may sway the analyses, thus strict criteria should be applied for a reliable identification of admixed ...
cell groups. Additionally, newer methods have emerged that define AS levels at the gene level rather than for specific AS events, such as SpliZ25. Nonetheless, these tools typically require known cell labels for differential analysis, and methods specifically designed for unsupervised clustering based...