Gene expression analysis of FACS-sorted cell populations from inflamed tissue from patients with IBD confirmed that several M4/M5 genes were highly expressed in CD16hi neutrophils and podoplanin (PDPN)+THY1+ stromal cells (Extended Data Figs. 5a,b and 3c; see Extended Data Fig. 6 for patie...
Sudden-onset fatal asthma: a distinct entity with few eosinophils and re- latively more neutrophils in the airway submucosa? Am Rev Respir Dis 1993; 148: 713±719. 52. Synek M, Anto JM, Beasley R, et al. Immunopathology of fatal soybean dust-induced asthma. Eur Respir J 1996; 9: 54...
Thrombin susceptibility to endogenous human proteases secreted by neutrophils during wounding was assessed by analyzing thein vitropeptide patterns generated by human neutrophil elastase (HNE) and cathepsin G (HCG). Both HNE and HCG cleaved thrombin completely, generating a large number of fragments (157...
(Immune_n1), monocytes, macrophage and neutrophils (Immune_n2), M1 macrophages and activated DCs which overlaps with IFN-response linked to MHC class I dependent antigen presentation (Immune_n3), M0 macrophages (Immune_n7), plasma cells and B-cells (Immune_n8), and mast cells (Immune_n10)...