E. Adlergrid.266100.30000 0001 2107 4242Division of Cardiology and Cardiovascular Institute, Department of MedicineUniversity of California San Diego La Jolla CA USANature Publishing Group UKNature Cardiovascular Research
Nature Genetics54,950–962 (2022)Cite this article 20kAccesses 114Altmetric Metrics Abstract More than 800 million people suffer from kidney disease, yet the mechanism of kidney dysfunction is poorly understood. In the present study, we define the genetic association with kidney function in 1.5 mill...
These data demonstrate the complexity of the diverse interactions between the microbiota, microbial ligands, and infection and highlight the region-specific nature of these interactions. Enteric Antiviral Response Consistent with the essential role of type III IFNs in the intestinal epithelium, treatment...
www.nature.com/scientificreports OPEN Received: 13 March 2019 Accepted: 7 June 2019 Published: xx xx xxxx On the potential of in vitro organ-chip models to define temporal pharmacokinetic- pharmacodynamic relationships Christopher W. McAleer1, Amy Pointon2, Christopher J. Long1, Rocky...
2017), and they have been much researched, not only for their DNA, but also on account of their iconic status as hunter-gatherer peoples living close to nature. Classic texts show San clans living nomadic lives in family groups without material possessions, tracking and bringing down their ...
Thanks to the combination of its architecture based on GPT-2 and GPT-3, and the different nature of data, GPT-Neo resulted to be suitable for multiple tasks in different domains, such as writing articles, completing sentences, and generating source codes. Medical Bot or MedBot is a ...
Notably, transduction of PAX6 in skin epithelial stem cells is sufficient to convert them to LSC-like cells, and upon transplantation onto eyes in a rabbit corneal injury model, these reprogrammed cells are able to replenish CECs and repair damaged corneal surface. These findings suggest a central...
That's what is so frustrating about nocturia. It's 1 symptom, and it has easily 20 different underpinnings, which means that it's so easy to find things that result in nocturia. But because of the multifactorial nature, we only make little increments when we fix each factor. In particular...
’ Furthermore, the results show the dual nature of these influencing factors, as they can either facilitate or hinder SC depending on whether their level is low or high. The results of this study offer valuable insights that enable practitioners to assess and promote SC in their organizations....
RNA splicing shapes the gene regulatory programs that underlie various physiological and disease processes. Here, we present the SCASL (single-cell clustering based on alternative splicing landscapes) method for interrogating the heterogeneity of RNA spl