In rodents there is a sialic acid gradient where the highest levels are at the villus tip and decrease as you move deeper into the crypt. (Jaswal et al., 1988). Given that rotaviruses use sialic acid as a co-receptor for entry, these findings might explain why rotavirus preferentially ...
Define and illustrate the term clearly and concisely. Write an equation to illustrate the meaning of the term. Lewis acid. Define and provide examples of the term Oxidizing agent. Describe the metallurgy of iron. What are the general properties of the d-transition metals?
In Alzheimer’s disease (AD), microglia form distinct cellular aggregates that play critical roles in disease progression, including Aβ plaque-associated microglia (PaM) and the newly identified coffin-like microglia (CoM). PaM are closely associated with amyloid-β (Aβ) plaques, while CoM are...
George Obiero2, Philip Bejon1,3, Jean Langhorne4, Abdirahman Abdi1 and Lynette Isabella Ochola‑Oyier1* Abstract Background Cumulative malaria parasite exposure in endemic regions often results in the acquisition of partial immunity and asymptomatic infections...
Define and illustrate the term clearly and concisely. Write an equation to illustrate the meaning of the term Lewis base. Differentiate between the terms "species reduced versus the reducing agent". Define the term pyranose form, and give an example. ...
George Obiero2, Philip Bejon1,3, Jean Langhorne4, Abdirahman Abdi1 and Lynette Isabella Ochola‑Oyier1* Abstract Background Cumulative malaria parasite exposure in endemic regions often results in the acquisition of partial immunity and asymptomatic infections...
Three alleles of one Nrf gene failed to complement a mutation in ndg-4, a gene that was previously identified in a screen for resistance to lethality from the lipoxygenase inhibitor nordihydroguaiaretic acid (NDG) (Shreffler et al. 1995). We found that NDG also caused nose muscle contraction...
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling the search for protein b
Define and illustrate the following terms clearly and concisely. Write an equation to illustrate the meaning of each term neutralization according to Lewis's theory. Describe the three main types of acid-base reactions: neutralization reactions, acid-metal reactions, and acid-metal oxide reactions. ...
Lewis acid. Define and illustrate the term clearly and concisely. Write an equation to illustrate the meaning of the term Lewis base. Define and illustrate the terms clearly and concisely inner transition elements. Define the term extensive property, and illustrate with a specific examp...