Integrative pharmacology is a discipline that builds an understanding of the inter-relationship between pharma- cokinetics (PK), the drug's time course for absorption, distribution, metabolism and excretion and pharmaco- dynamics (PD), the biological effect of a drug. In drug discovery, this ...
Anti-PD-1, anti-programmed death-1; anti-CTLA-4, anti-cytotoxic T lymphocyte antigen-4; LDH, lactate dehydrogenase; AJCC, American Joint Committee on Cancer; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; PFS, progression-free survival; OS, overall...
Here, we set the mean immune cell velocity to 10 μm min−1, which results in a lattice move probability of hr = 0.37 per min−1. The waiting time for immune cell movement follows an exponential probability distribution. Immune cell motility is updated 60 times (every minute) per ...
Low standard deviation values across all cases affirm a narrow distribution of values. Fig. 9 Mean suitability and standard deviation values for each of four forest uses (primary and secondary FUS for a 100-year simulation) Full size image The results of the robustness analysis, comparing the ...
Suppose X and Y have the following joint density function: Find the cumulative distribution function of X and Y. Suppose that X and Y have a joint probability density function given by: (a) Find the conditional density of X given Y = y...
To elicit, for example, the 50th percentile corresponding to the probability distribution of the importance level of the “living fences” activity, after providing the expert with pedagogical information about the concept of living fences, their environmental, social, and economic benefits, and basic...