Here we describe a subset of intestinal stromal cells, named MAP3K2-regulated intestinal stromal cells (MRISCs), and show that they are the primary cellular source of the WNT agonist R-spondin 1 following intestinal injury in mice. MRISCs, which are epigenetically and transcriptomically distinct...
Furthermore, the significant signal for isolation-by-distance found in B.argenteum within Tenerife points to the substantial role of genetic drift in establishing the observed patterns of genetic variation. Together, the results support the hypothesis that B.argenteum is native on Tenerife; although ...
The isolation of nuclei was accomplished using the OmniATAC protocol54 or the S2 Singulator (four samples) and is described further in the Supplementary methods. Following nuclei dissociation, scATAC-seq targeting 9,000 cells per sample was performed using Chromium Next GEM Single Cell ATAC Library...
While early studies that investigated specific RNA–protein interactions in isolation laid the foundation for our understanding of the existence of molecular machines to assemble and process RNAs, there is a more recent appreciation of the importance of individual RNA–protein interactions that contribute...
We are reporting the identification, isolation, and detailed characterization of the most primitive mesenchymal progenitor cells in the adult murine bone marrow, based on the expression of stage-specific embryonic antigen–1 (SSEA-1). This primitive subset can be identified in mesenchymal cell ...
Genetic connectivity among populations can be estimated by evaluation of metrics such as of isolation by distance (IBD) signatures and population structure. Such metrics are influenced not only by geographic distance and barriers to dispersal but also by the life-history characteristics of the species...
Detailed knowledge about this important process now exists for different brain regions in rodent and monkey models as well as in t... Barth,G Peter - 《Canadian Journal of Neurological Sciences》 被引量: 755发表: 1987年 Reiner, O. et al. Isolation of a Miller-Dieker lissencephaly gene ...
A set of temperature-sensitive Saccharomyces cerevisiae mutants designated cly (for cell lysis) 1–8 because the cells lyse at high temperature was isolated in a large screen for yeast temperature-sensitive mutations (Hartwell, 1967). Here we report the isolation of two plasmids, containing inserts...
Cell density (b) and sucrose levels in culture supernatants (c) were measured. Error bars are standard deviation of 8 biological replicates. For characterization of cyanobacteria in CoYBG-11 see Additional file 1: Figure S1. d Heterotroph growth in isolation was characterized via growth rate in...
LHC participated in the sample collections and RNA and DNA isolations and quality controls, carried out the quantitative PCR studies, participated in the design of the study and in the bioinformatics and helped to draft the manuscript. IS participated in the design of the study and carried out ...