Computer programs are great at replicating but creating value outside their existing parameters is more challenging. Putting a human in the loop to reign in unacceptable levels of variation based upon judgment is a good way to utilize both element’s strengths....
Human leukaemia inhibitory factor (hLIF) binds to both human and mouse LIF receptors (LIF-R), while mouse LIF (mLIF) binds only to mouse LIF-R. Moreover, hLIF binds with higher affinity to the mLIF-R than does mLIF. In order to define the regions of the hLIF molecule responsible ...
In this study, the researchers characterize the multi-hierarchical genome organization of human LSCs, including chromosomal compartments, TADs and high-resolution chromatin loops. The combination of chromatin organization, epigenome, TF occupancy and transcriptome creates comprehensive 3D epigenomic landscapes t...
Here, we investigated a panel of MSP-1-specific naturally acquired human monoclonal antibodies (hmAbs). Structures of multiple hmAbs with diverse neutralizing potential in complex with MSP-1 revealed the epitope of a potent strain-transcending hmAb. This neutralizing epitope overlaps with the ...
What is at the inferior end of the sacrum? In anatomical terms, are the kidneys inferior to the lungs? What is the smallest blood vessel? Which are the thinnest blood vessels? What is the smallest artery in human body? What is the ramus coronary artery?
We excluded gRNAs that had more than two perfect matches in the GRCh38 human genome (n = 134), and gRNAs with <100 read counts in the plasmid or any time zero sample in the screens (n = 27). For the few hit gRNAs with two perfect matches in the genome, we confirmed ...
("Human","cat"=>array("Lion","Tiger","Jaguar"),"Elephant","Monkey"),"reptiles"=>array("snake"=>array("Cobra"=>array("King Cobra","Egyptian cobra"),"Viper","Anaconda"),"Crocodile","Dinosaur"=>array("T-rex","Alamosaurus")));// Count and print values in nested array$result=...
IBM is committed to compliance with theAccessibility for Ontarians with Disabilities Act (AODA),Accessibility for Manitobans Act (AMA)and theOntario Human Rights Codein the recruitment process. If you are an individual with a disability that requires a reasonable accommodation or are unable or limited...
The alpha-melanocyte-stimulating hormone (alphaMSH) receptor (MC1R) is a major determinant of mammalian skin and hair pigmentation. Binding of alphaMSH to MC1R in human melanocytes stimulates cell proliferation and synthesis of photoprotective eumelanin pigments. Certain MC1R alleles have been associat...
aIn order to meet the FCTC specification in terms of reducing the planting of tobacco, the government has been working on appropriate methods for the diversification of areas cultivated with tobacco. The first proposals were presented in September 2009 in New Delhi, India. However, few human and...