Because germline TP53 mutations are the primary cause of Li–Fraumeni syndrome (LFS), which is a highly cancer-prone autosomal dominant disorder28, we theorized that mutant p53 fitness relates to the time to first tumour formation in patients with LFS. We plotted Kaplan–Meier curves showing the...
For instance, flipping the preselected, default choice (the choice people automatically receive if they do not actively indicate a preference) from "opt out" to "opt in" can increase participation rates in organ donation programs and employee savings plans. Social norms marketing. People often ...