Elowitz, M.B., Levine, A.J., Siggia, E.D., et al.: Stochastic Gene Expression in a Single Cell. Science 297, 1183–1186 (2002) ArticleGoogle Scholar Etzkowitz, H., Leydesdorff, L.: The dynamics of innovation: from National Systems and “Mode 2” to a Triple Helix of university–...
Identification of a conserved N-capping box important for the structural autonomy of the prion alpha 3-helix: the disease associated D202N mutation destabilizes the helical conformationInt. J. Immunopathol. Pharmacol.10.1177/039463200501800111 Gallo, M., Paludi, D., Cicero, D.O., Chiovitti, K....
The EF-hand proteins, which is the topic of this review, consist of proteins showing a general structural principle in the calcium-binding domain called the EF-hand (Kretsinger, 1981). They are composed of a stretch of amino acids having a helix-loop-helix structure. The EF-hand family ...
2B. In order to understand perturbations in the overall secondary structures, we calculated percentage structural changes for α-helix and β-sheets for target mutations compared to wild-type. These models indicate no significant changes to the overall TUBA4A secondary structures predicted for the ...
We describe a mechanism connecting the adaptive behavior of the bacterial mechanosensitive channel MscS to the flexibility of the pore-lining helix TM3. Simulated expansion of the channel structure revealed straightening of a characteristic kink near Gly
Describe briefly the difference between a-helix and b-pleated sheet conformation. What is a melt curve and what does it indicate? How does calmodulin-binding calcium result in cross-bridge attachment? How does PCR relate to biomedical engineering? What is meant by semi-conservative replicatio...
Using deletion analysis, we have defined the minimal domain in GFP required for fluorescence to amino acids 7–229. This domain starts at the middle of the first small α helix at the N terminus of GFP and ends immediately following the last β sheet. Studies of the amino acids at both ...
what is the most abundant element in the human body by mass (midterm question) oxygen what holds the strands of a double helix dna strand (midterm question) hydrogen bonds strongest bonds metallic, covalent, and ionic singe covalent bond ethanol double covalent ethylene property of water cohesive...
Using deletion analysis, we have defined the minimal domain in required for fluorescence to amino acids 7-229. This domain starts at the middle of the first small alpha helix at the N terminus of and ends immediately following the last beta sheet. Studies of the amino acids...
The SPEAR element is near the virus 3′-end triple-helix junction necessary for recognition by the replication-transcription complex (RTC). Thus, the PPMOs might reduce viral titer by a SPEAR element-independent mechanism in which binding of the polymerase to the RNA is blocked, thus reducing ...